Poly(ethylene glycol)-poly(l-glutamine) (PEG-PLGA) copolymer EA-G2 (or EA-G1) was prepared by aminolysis of poly(ethylene glycol)-poly(l-benzyl glutamate) (PEG-PBLG) using PAMAM G2 (or G1). The chemical structure of PEG-PLGA was confirmed by FT-IR, 1H-NMR, DSC and GPC. The performances of the EA-G2 (or EA-G1) were assayed by enzyme degradation, MTT method and agarose gel electrophoresis. The particle size, zeta potential and morphology of EA-G2 (or EA-G1)/pDNA complexes were inspected by DLS and AFM. The cellular uptake mechanism was evaluated by endocytic inhibiting test, cell uptake test and observation of CLSM. 

AGP antibody

20-S7931G000-S7 10 ml
EUR 133
Description: Goat polyclonal Human alpha 1 Acid Glycoprotein antibody

Alpha1-AGP/ Rat Alpha1- AGP ELISA Kit

ELA-E0816r 96 Tests
EUR 886

8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

DLR-8-OHdG-Ge-48T 48T
EUR 469
Description: A competitive inhibition quantitative ELISA assay kit for detection of 8-Hydroxydeoxyguanosine (8-OHdG) in samples from serum, plasma or other biological fluids.

8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

DLR-8-OHdG-Ge-96T 96T
EUR 608
Description: A competitive inhibition quantitative ELISA assay kit for detection of 8-Hydroxydeoxyguanosine (8-OHdG) in samples from serum, plasma or other biological fluids.

5-50UL 8-CHANNEL, DIGITAL PIPETTOR

AP-8-50 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

0.5-10UL 8-CHANNEL, DIGITAL PIPETTOR

AP-8-10 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

20-200UL 8-CHANNEL, DIGITAL PIPETTOR

AP-8-200 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

50-300UL 8-CHANNEL, DIGITAL PIPETTOR

AP-8-300 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RD-8-OHdG-Ge-48Tests 48 Tests
EUR 467

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RD-8-OHdG-Ge-96Tests 96 Tests
EUR 646

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RDR-8-OHdG-Ge-48Tests 48 Tests
EUR 488

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RDR-8-OHdG-Ge-96Tests 96 Tests
EUR 676

pAAV-DJ/8 Vector

VPK-420-DJ-8 10 µg
EUR 647
Description: The pAAV-DJ/8 vector contains the rep and cap genes required to generated recombinant AAV of serotype DJ/8. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-DJ/8 packaging.

Bovine AGP ELISA Kit

E-10AGP 1 x 96 well plate
EUR 461

Rat AGP ELISA Kit

E-25AGP 1 x 96 well plate
EUR 441

Chicken AGP ELISA Kit

E-30AGP 1 x 96 well plate
EUR 441

Dog AGP ELISA Kit

E-40AGP 1 x 96 well plate
EUR 492

Human AGP ELISA Kit

E-80AGP 1 x 96 well plate
EUR 370

PSA (Prostate-specific antigen) ELISA test

8 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PSA (Prostate-specific antigen)

Sheep A1-AGP ELISA Kit

ESA0695 96Tests
EUR 521

Mouse A1-AGP ELISA Kit

EMA0695 96Tests
EUR 521

Monkey A1-AGP ELISA Kit

EMKA0695 96Tests
EUR 521

Porcine A1-AGP ELISA Kit

EPA0695 96Tests
EUR 521

Rat A1-AGP ELISA Kit

ERA0695 96Tests
EUR 521

Rabbit A1-AGP ELISA Kit

ERTA0695 96Tests
EUR 521

Anserini A1-AGP ELISA Kit

EAA0695 96Tests
EUR 521

Goat A1-AGP ELISA Kit

EGTA0695 96Tests
EUR 521

Canine A1-AGP ELISA Kit

ECA0695 96Tests
EUR 521

Chicken A1-AGP ELISA Kit

ECKA0695 96Tests
EUR 521

Human A1-AGP ELISA Kit

EHA0695 96Tests
EUR 521

Bovine A1-AGP ELISA Kit

EBA0695 96Tests
EUR 521

AGP ELISA Kit (Bovine) (OKCD06846)

OKCD06846 96 Wells
EUR 1040
Description: Description of target: Functions as transport protein in the blood stream.UniRule annotation;Species reactivity: Bovine;Application: ELISA;Assay info: ;Sensitivity: < 7.0ng/mL

AAV-DJ/8 Helper Free Packaging System

VPK-400-DJ-8 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-DJ/8 Helper Free Expression System

VPK-410-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

scAAV-DJ/8 Helper Free Expression System

VPK-430-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Promoterless Expression System

VPK-411-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

General 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) ELISA Kit

RD-8-epi-PGF2a-Ge-48Tests 48 Tests
EUR 467

General 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) ELISA Kit

RD-8-epi-PGF2a-Ge-96Tests 96 Tests
EUR 646

Guinea Pig A1-AGP ELISA Kit

EGA0695 96Tests
EUR 521

AXYGEN® 8-WELL COMB FOR USE WITH 10 CM GEL BOX, 1.0 MM THICKNESS

HGB10-8-1 1/pk
EUR 59
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.0 MM THICKNESS

HGB15-8-1 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-8-15 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 7 CM GEL BOX, 0.75 MM THICKNESS

HGB7-8-075 1/pk
EUR 54
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 7 CM GEL BOX, 1.0 MM THICKNESS

HGB7-8-1 1/pk
EUR 54
Description: Lab Equipment; Axygen Branded EQ

AXYPET 50-300UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X4

AP-8-300-ALT 1/pk
EUR 456
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 50-300UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X10

AP-8-300-STD 1/pk
EUR 507
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 5-50UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X4

AP-8-50-ALT 1/pk
EUR 456
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 5-50UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X10

AP-8-50-STD 1/pk
EUR 507
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 0.5-10UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X4

AP-8-10-ALT 1/pk
EUR 456
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 0.5-10UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X10

AP-8-10-STD 1/pk
EUR 507
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 20-200UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X4

AP-8-200-ALT 1/pk
EUR 456
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET 20-200UL 8-CHANNEL, DIGITAL PIPETTOR ISO17025 3X10

AP-8-200-STD 1/pk
EUR 507
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AAV-DJ/8 Helper Free Bicistronic Expression System (Puro)

VPK-415-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Neo)

VPK-416-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Hygro)

VPK-417-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (GFP)

VPK-418-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Blasticidin)

VPK-419-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

MINI TUBE, 8 STRIP, POLYPROPYLENE, 1.1 ML, CLEAR, NONSTERILE, BULK

MTS-11-8-C 120/pk
EUR 140
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

Alpha 1 Acid Glycoprotein (A1-AGP), bovine

A1AG20-N 1 mg
EUR 164

Alpha 1 Acid Glycoprotein (A1-AGP), Rabbit

A1AG23-N-25 25 ug
EUR 286

Alpha 1 Acid Glycoprotein (A1-AGP), Turkey

A1AG24-N-100 100 ug
EUR 164

anti-α1-acid glycoprotein (AGP)(29A1)

LF-MA0167 100 ul
EUR 334
Description: Mouse monoclonal to α1-acid glycoprotein (AGP)

AXYGEN® AXYPET® PRO 30-300 ΜL, 8 CHANNEL PIPETTOR, AUTOCLAVABLE

AP-8-300-P 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYGEN® AXYPET® PRO 5-50 ΜL, 8 CHANNEL PIPETTOR, AUTOCLAVABLE

AP-8-50-P 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYGEN® AXYPET® PRO 0.5-10 ΜL, 8 CHANNEL PIPETTOR, AUTOCLAVABLE

AP-8-10-P 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYGEN® AXYPET® PRO 20-200 ΜL, 8 CHANNEL PIPETTOR, AUTOCLAVABLE

AP-8-200-P 1/pk
EUR 455
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Porcine α1-Acid glycoprotein,α1-AGP ELISA Kit

GA-E0068PC-48T 48T
EUR 364

Porcine α1-Acid glycoprotein,α1-AGP ELISA Kit

GA-E0068PC-96T 96T
EUR 590

Rat α1-Acid glycoprotein(α1-AGP)ELISA Kit

GA-E0093RT-48T 48T
EUR 317

Rat α1-Acid glycoprotein(α1-AGP)ELISA Kit

GA-E0093RT-96T 96T
EUR 496

Human α1-Acid glycoprotein(α1-AGP)ELISA Kit

GA-E1792HM-48T 48T
EUR 289

Human α1-Acid glycoprotein(α1-AGP)ELISA Kit

GA-E1792HM-96T 96T
EUR 466

Human ?1-Acid glycoprotein,?1-AGP ELISA Kit

201-12-1776 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Alpha-1-Acid-Glycoprotein (Orosomucoid, AGP) Antibody

12011-05011 150 ug
EUR 217

Human alpha-1-Acid-Glycoprotein (Orosomucoid, AGP) Antibody

32220-05111 150 ug
EUR 261

Alpha 1 Acid Glycoprotein (A1-AGP), Human Plasma

A1AG15-N 1 mg
EUR 164

Mouse α1-AGP(α1-Acid glycoprotein) ELISA Kit

EM1448 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 3.75 ng/ml

Porcine α1-AGP(α1-Acid Glycoprotein) ELISA Kit

EP0214 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Pig;Sensitivity: 0.094 ng/ml

Rat α1-Acid glycoprotein(α1-AGP)ELISA Kit

QY-E11560 96T
EUR 361

Mouse α1-Acid glycoprotein(α1-AGP)ELISA Kit

QY-E21637 96T
EUR 361

Human α1-Acid glycoprotein(α1-AGP)ELISA Kit

QY-E04459 96T
EUR 361

Rat α1-AGP(α1-Acid Glycoprotein) ELISA Kit

ER1432 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 3.75 ng/ml

Bovine α1-Acid glycoprotein,α1-AGP ELISA Kit

CN-00487B1 96T
EUR 458

Bovine α1-Acid glycoprotein,α2-AGP ELISA Kit

CN-00487B2 48T
EUR 307

Rat α1-Acid glycoprotein,α1-AGP ELISA Kit

CN-01787R1 96T
EUR 473

Rat α1-Acid glycoprotein,α1-AGP ELISA Kit

CN-01787R2 48T
EUR 323

Mouse α1-Acid glycoprotein,α1-AGP ELISA Kit

CN-02666M1 96T
EUR 464

Mouse α1-Acid glycoprotein,α1-AGP ELISA Kit

CN-02666M2 48T
EUR 313

MINI TUBE, 8 STRIP, POLYPROPYLENE, 1.1 ML, CLEAR, RACKED, NONSTERILE, BULK

MTS-11-8-C-R 120/pk
EUR 280
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

CLIA kit for Mouse ?1-AGP (?1-Acid glycoprotein)

E-CL-M0687 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Mouse ?1-AGP (?1-Acid glycoprotein) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Rat ?1-AGP (?1-Acid Glycoprotein)

E-CL-R0695 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Rat ?1-AGP (?1-Acid Glycoprotein) in samples from Serum, Plasma, Cell supernatant

Alpha 1 Acid Glycoprotein (A1-AGP), Pig/Porcine/Swine

A1AG22-N-100 100 ug
EUR 164

Human Alpha-1-Acid Glycoprotein ELISA Kit (AGP 1)

RK00779 96 Tests
EUR 521

Chicken a1-Acid Glycoprotein (a-1-AGP) ELISA Kit

QY-E80114 96T
EUR 426

Anti-GFAP Antibody (monoclonal, 3F2)

M00213-8 100ug/vial
EUR 334

Anti-Caspase-3 Rabbit Monoclonal Antibody, Clone#RM250

M00334-8 100ul
EUR 375
Description: Anti-Caspase-3 Rabbit Monoclonal Antibody, Clone#RM250 tested in WB, IHC, reactive to Human