Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes

CaveolinThree variants related to arrhythmogenic cardiomyopathy and muscular dystrophy can disrupt post-Golgi floor trafficking. As Caveolin1 was not too long ago recognized in cardiomyocytes, we hypothesize that conserved isoform-specific protein/protein interactions orchestrate distinctive cardiomyocyte microdomain capabilities. To analyze the Caveolin1 versus CaveolinThree interactome, we employed unbiased live-cell proximity proteomic, isoform-specific affinity, and complexome profiling mass spectrometry methods. We display the physiological relevance and loss-of-function mechanism of a novel CaveolinThree interactor in gene-edited human iPSC-cardiomyocytes.

To determine differential Caveolin1 versus CaveolinThree protein interactions and to outline the molecular foundation of cardiac CAV3 loss-of-function. Combining steady isotope labeling with proximity proteomics, we utilized mass spectrometry to display for putative CaveolinThree interactors in dwelling cardiomyocytes. Isoform-specific affinity proteomic and co-immunoprecipitation experiments confirmed the monocarboxylate transporter McT1 versus aquaporin1, respectively, as CaveolinThree or Caveolin1 particular interactors in cardiomyocytes. Superresolution STED microscopy confirmed distinct Caveolin1 versus CaveolinThree cluster distributions in cardiomyocyte transverse tubules.

CRISPR/Cas9-mediated CaveolinThree knock-out uncovered a stabilizing function for McT1 floor expression, proton-coupled lactate shuttling, elevated late Na+ currents, and early afterdepolarizations in human iPSC-derived cardiomyocytes. Complexome profiling confirmed that McT1 and the Na,Okay-ATPase kind labile protein assemblies with the multimeric CaveolinThree complicated. Combining the strengths of proximity and affinity proteomics, we recognized isoform-specific Caveolin1 versus CaveolinThree binding companions in cardiomyocytes.

McT1 represents a novel class of metabolically related Caveolin3-specific interactors near mitochondria in cardiomyocyte transverse tubules. CaveolinThree knock-out uncovered a beforehand unknown function for practical stabilization of McT1 in the floor membrane of human cardiomyocytes. Strikingly, CaveolinThree poor cardiomyocytes exhibit motion potential prolongation and instability, reproducing human reentry arrhythmias in silico. Given that lactate is a significant substrate for stress adaption each in the wholesome and the diseased human coronary heart, future research of conserved McT1/CaveolinThree interactions might present rationales to focus on this muscle-specific meeting operate therapeutically.

The Inflammatory Cytokine IL-3 Hampers Cardioprotection Mediated by Endothelial Cell-Derived Extracellular Vesicles Possibly by way of Their Protein Cargo

The organic relevance of extracellular vesicles (EV) launched in an ischemia/reperfusion setting remains to be unclear. We hypothesized that the inflammatory microenvironment prevents cardioprotection mediated by endothelial cell (EC)-derived extracellular vesicles. The results of naïve EC-derived EV (eEV) or eEV launched in response to interleukin-3 (IL-3) (eEV-IL-3) had been evaluated in cardiomyoblasts (H9c2) and rat hearts. In transwell assay, eEV protected the H9c2 uncovered to hypoxia/reoxygenation (H/R) extra effectively than eEV-IL-3.

Conversely, solely eEV instantly protected H9c2 cells to H/R-induced harm. Consistent with this latter remark, eEV, however not eEV-IL-3, exerted helpful results in the entire coronary heart. Protein profiles of eEV and eEV-IL-3, established utilizing label-free mass spectrometry, demonstrated that IL-Three drives adjustments in eEV-IL-Three protein cargo. Gene ontology evaluation revealed that each eEV and eEV-IL-Three had been geared up with full cardioprotective equipment, together with the Nitric Oxide Signaling in the Cardiovascular System. eEV-IL-Three had been additionally enriched in the endothelial-nitric oxide-synthase (eNOS)-antagonist caveolin-1 and proteins associated to the inflammatory response.

In vitro and ex vivo experiments demonstrated {that a} practical Mitogen-Activated Protein Kinase Kinase (MEK1/2)/eNOS/guanylyl-cyclase (GC) pathway is required for eEV-mediated cardioprotection. Consistently, eEV had been discovered enriched in MEK1/2 and in a position to induce the expression of B-cell-lymphoma-2 (Bcl-2) and the phosphorylation of eNOS in vitro. We conclude that an inflammatory microenvironment containing IL-Three adjustments the eEV cargo and impairs eEV cardioprotective motion.

Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes

Nitric oxide modulates bone anabolism by means of regulation of osteoblast glycolysis and differentiation

Previous research have proven that nitric oxide (NO) dietary supplements might stop bone loss and fractures in preclinical fashions of estrogen deficiency. However, the mechanisms by which NO modulates bone anabolism stay largely unclear. Argininosuccinate lyase (ASL) is the one mammalian enzyme able to synthesizing arginine, the only precursor for nitric oxide synthase (NOS)-dependent NO synthesis. Moreover, ASL can also be required for channeling extracellular arginine to NOS for NO manufacturing. ASL deficiency (ASLD) is thus a mannequin to check cell-autonomous, NOS-dependent NO deficiency.

Here, we report that lack of ASL led to decreased NO manufacturing and impairment of osteoblast differentiation. Mechanistically, the bone phenotype was a minimum of in half pushed by the lack of NO-mediated activation of the glycolysis pathway in osteoblasts that led to decreased osteoblast differentiation and performance. Heterozygous deletion of Caveolin-1, a unfavorable regulator of NO synthesis, restored NO manufacturing, osteoblast differentiation, glycolysis, and bone mass in a hypomorphic mouse mannequin of ASLD. The translational significance of those preclinical research was additional reiterated by research carried out in induced pluripotent stem cells (iPSCs) from a person with ASLD.

Rat Caveolin 1 ELISA kit

E02C0407-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin 1 ELISA kit

E02C0407-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin-1 ELISA kit

E02C0700-192T 192 tests
EUR 1270
Description: A Sandwich ELISA for quantitative measurement of Rat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin-1 ELISA kit

E02C0700-48 1 plate of 48 wells
EUR 520
Description: A Sandwich ELISA for quantitative measurement of Rat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin-1 ELISA kit

E02C0700-96 1 plate of 96 wells
EUR 685
Description: A Sandwich ELISA for quantitative measurement of Rat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin 1 (CAV1) ELISA Kit

SEA214Ra-10x96wellstestplate 10x96-wells test plate
EUR 4626.78
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Caveolin 1 (CAV1) in serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

SEA214Ra-1x48wellstestplate 1x48-wells test plate
EUR 468.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Caveolin 1 (CAV1) in serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

SEA214Ra-1x96wellstestplate 1x96-wells test plate
EUR 626.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Caveolin 1 (CAV1) in serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

SEA214Ra-5x96wellstestplate 5x96-wells test plate
EUR 2520.06
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Caveolin 1 (CAV1) in serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

4-SEA214Ra
  • EUR 4677.00
  • EUR 2471.00
  • EUR 627.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Caveolin 1 (CAV1) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.

Rat Caveolin 1 ELISA Kit (CAV1)

RK03552 96 Tests
EUR 521

Rat Caveolin 1 (CAV1) ELISA Kit

RD-CAV1-Ra-48Tests 48 Tests
EUR 511

Rat Caveolin 1 (CAV1) ELISA Kit

RD-CAV1-Ra-96Tests 96 Tests
EUR 709

Rat Cav1/ Caveolin-1 ELISA Kit

E0163Ra 1 Kit
EUR 571

Rat Caveolin 1 (CAV1) ELISA Kit

DLR-CAV1-Ra-48T 48T
EUR 508
Description: A sandwich quantitative ELISA assay kit for detection of Rat Caveolin 1 (CAV1) in samples from serum, plasma or other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

DLR-CAV1-Ra-96T 96T
EUR 661
Description: A sandwich quantitative ELISA assay kit for detection of Rat Caveolin 1 (CAV1) in samples from serum, plasma or other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

abx570323-96tests 96 tests
EUR 707

Rat Caveolin 1 (CAV1) ELISA Kit

20-abx155317
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Caveolin 1 (CAV1) ELISA Kit

abx256234-96tests 96 tests
EUR 707

Rat Caveolin 1 (CAV1) ELISA Kit

RDR-CAV1-Ra-48Tests 48 Tests
EUR 534

Rat Caveolin 1 (CAV1) ELISA Kit

RDR-CAV1-Ra-96Tests 96 Tests
EUR 742

ELISA kit for Rat Caveolin-1

EK1495 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat Caveolin-1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Rat Caveolin-1, CAV ELISA Kit

ELA-E0214r 96 Tests
EUR 886

Rat Caveolin-1, Cav-1 ELISA KIT

CSB-E04837r-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Rat Caveolin-1, Cav-1 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Caveolin-1, Cav-1 ELISA KIT

1-CSB-E04837r
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Caveolin-1, Cav-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Caveolin-1(Cav-1)ELISA Kit

GA-E0362RT-48T 48T
EUR 317

Rat Caveolin-1(Cav-1)ELISA Kit

GA-E0362RT-96T 96T
EUR 496

Rat Cav-1(Caveolin-1) ELISA Kit

ER0256 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 9.375pg/ml

Rat Caveolin-1(Cav-1)ELISA Kit

QY-E11290 96T
EUR 361

Rat Caveolin-1,Cav-1 ELISA KIT

CN-02003R1 96T
EUR 461

Cav-1 ELISA Kit| Rat Caveolin-1 ELISA Kit

EF017146 96 Tests
EUR 689

ELISA kit for Rat CAV1 (Caveolin 1)

ELK2333 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Caveolin 1 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Rat Caveolin-1,Cav-2 ELISA KIT

CN-02003R2 48T
EUR 310

ELISA kit for Rat CAV-1 (Caveolin-1)

E-EL-R0175 1 plate of 96 wells
EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Rat CAV-1 (Caveolin-1) in samples from Serum, Plasma, Cell supernatant

Caveolin-1 Cell ELISA Kit

abx595098-96tests 96 tests
EUR 637

Human Caveolin 1 ELISA kit

E01C0407-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin 1 ELISA kit

E01C0407-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin 1 ELISA kit

E01C0407-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin 1 ELISA kit

E03C0407-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin 1 ELISA kit

E03C0407-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin 1 ELISA kit

E03C0407-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin-1 ELISA kit

E03C0700-192T 192 tests
EUR 1270
Description: A Sandwich ELISA for quantitative measurement of Mouse Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin-1 ELISA kit

E03C0700-48 1 plate of 48 wells
EUR 520
Description: A Sandwich ELISA for quantitative measurement of Mouse Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin-1 ELISA kit

E03C0700-96 1 plate of 96 wells
EUR 685
Description: A Sandwich ELISA for quantitative measurement of Mouse Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin-1 ELISA kit

E01C0700-192T 192 tests
EUR 1270
Description: A Sandwich ELISA for quantitative measurement of Human Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin-1 ELISA kit

E01C0700-48 1 plate of 48 wells
EUR 520
Description: A Sandwich ELISA for quantitative measurement of Human Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin-1 ELISA kit

E01C0700-96 1 plate of 96 wells
EUR 685
Description: A Sandwich ELISA for quantitative measurement of Human Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin 1 ELISA kit

E07C0407-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin 1 ELISA kit

E07C0407-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin 1 ELISA kit

E07C0407-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin-1 ELISA kit

E07C0700-192T 192 tests
EUR 1270
Description: A Sandwich ELISA for quantitative measurement of Porcine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin-1 ELISA kit

E07C0700-48 1 plate of 48 wells
EUR 520
Description: A Sandwich ELISA for quantitative measurement of Porcine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin-1 ELISA kit

E07C0700-96 1 plate of 96 wells
EUR 685
Description: A Sandwich ELISA for quantitative measurement of Porcine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin 1 ELISA kit

E06C0407-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin 1 ELISA kit

E06C0407-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin 1 ELISA kit

E06C0407-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin-1 ELISA kit

E06C0700-192T 192 tests
EUR 1270
Description: A Sandwich ELISA for quantitative measurement of Goat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin-1 ELISA kit

E06C0700-48 1 plate of 48 wells
EUR 520
Description: A Sandwich ELISA for quantitative measurement of Goat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin-1 ELISA kit

E06C0700-96 1 plate of 96 wells
EUR 685
Description: A Sandwich ELISA for quantitative measurement of Goat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin 1 ELISA kit

E04C0407-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin 1 ELISA kit

E04C0407-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin 1 ELISA kit

E04C0407-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin-1 ELISA kit

E04C0700-192T 192 tests
EUR 1270
Description: A Sandwich ELISA for quantitative measurement of Rabbit Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin-1 ELISA kit

E04C0700-48 1 plate of 48 wells
EUR 520
Description: A Sandwich ELISA for quantitative measurement of Rabbit Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin-1 ELISA kit

E04C0700-96 1 plate of 96 wells
EUR 685
Description: A Sandwich ELISA for quantitative measurement of Rabbit Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin 1 ELISA kit

E08C0407-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin 1 ELISA kit

E08C0407-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin 1 ELISA kit

E08C0407-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin-1 ELISA kit

E08C0700-192T 192 tests
EUR 1270
Description: A Sandwich ELISA for quantitative measurement of Canine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin-1 ELISA kit

E08C0700-48 1 plate of 48 wells
EUR 520
Description: A Sandwich ELISA for quantitative measurement of Canine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin-1 ELISA kit

E08C0700-96 1 plate of 96 wells
EUR 685
Description: A Sandwich ELISA for quantitative measurement of Canine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin 1 ELISA kit

E09C0407-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin 1 ELISA kit

E09C0407-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin 1 ELISA kit

E09C0407-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin-1 ELISA kit

E09C0700-192T 192 tests
EUR 1270
Description: A Sandwich ELISA for quantitative measurement of Monkey Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin-1 ELISA kit

E09C0700-48 1 plate of 48 wells
EUR 520
Description: A Sandwich ELISA for quantitative measurement of Monkey Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin-1 ELISA kit

E09C0700-96 1 plate of 96 wells
EUR 685
Description: A Sandwich ELISA for quantitative measurement of Monkey Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Anti-Caveolin-1/CAV1 Antibody (monoclonal, 12C7)

M00179-1 100ug/vial
EUR 334

Rat Caveolin 1 (CAV1) CLIA Kit

20-abx491229
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Caveolin-1 (CAV-1) CLIA Kit

abx196798-96tests 96 tests
EUR 825

Dog Caveolin 1 (CAV1) ELISA Kit

SEA214Ca-10x96wellstestplate 10x96-wells test plate
EUR 4862.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Dog Caveolin 1 (CAV1) in serum, plasma, tissue homogenates and other biological fluids.

Dog Caveolin 1 (CAV1) ELISA Kit

SEA214Ca-1x48wellstestplate 1x48-wells test plate
EUR 488.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Dog Caveolin 1 (CAV1) in serum, plasma, tissue homogenates and other biological fluids.

Dog Caveolin 1 (CAV1) ELISA Kit

SEA214Ca-1x96wellstestplate 1x96-wells test plate
EUR 654.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Dog Caveolin 1 (CAV1) in serum, plasma, tissue homogenates and other biological fluids.

Dog Caveolin 1 (CAV1) ELISA Kit

SEA214Ca-5x96wellstestplate 5x96-wells test plate
EUR 2644.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Dog Caveolin 1 (CAV1) in serum, plasma, tissue homogenates and other biological fluids.

Dog Caveolin 1 (CAV1) ELISA Kit

4-SEA214Ca
  • EUR 4913.00
  • EUR 2595.00
  • EUR 655.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Dog Caveolin 1 (CAV1) in samples from Serum, plasma, tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Gallus Caveolin 1 (CAV1) ELISA Kit

SEA214Ga-10x96wellstestplate 10x96-wells test plate
EUR 4626.78
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Gallus Caveolin 1 (CAV1) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Gallus Caveolin 1 (CAV1) ELISA Kit

SEA214Ga-1x48wellstestplate 1x48-wells test plate
EUR 468.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Gallus Caveolin 1 (CAV1) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Gallus Caveolin 1 (CAV1) ELISA Kit

SEA214Ga-1x96wellstestplate 1x96-wells test plate
EUR 626.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Gallus Caveolin 1 (CAV1) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Gallus Caveolin 1 (CAV1) ELISA Kit

SEA214Ga-5x96wellstestplate 5x96-wells test plate
EUR 2520.06
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Gallus Caveolin 1 (CAV1) in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Gallus Caveolin 1 (CAV1) ELISA Kit

4-SEA214Ga
  • EUR 4677.00
  • EUR 2471.00
  • EUR 627.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Gallus Caveolin 1 (CAV1) in samples from Serum, plasma, tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Caveolin 1 (CAV1) ELISA Kit

SEA214Hu-10x96wellstestplate 10x96-wells test plate
EUR 4273.35
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Caveolin 1 (CAV1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Caveolin 1 (CAV1) ELISA Kit

SEA214Hu-1x48wellstestplate 1x48-wells test plate
EUR 439.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Caveolin 1 (CAV1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Caveolin 1 (CAV1) ELISA Kit

SEA214Hu-1x96wellstestplate 1x96-wells test plate
EUR 585.1
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Caveolin 1 (CAV1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Caveolin 1 (CAV1) ELISA Kit

SEA214Hu-5x96wellstestplate 5x96-wells test plate
EUR 2332.95
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Caveolin 1 (CAV1) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Caveolin 1 (CAV1) ELISA Kit

4-SEA214Hu
  • EUR 4324.00
  • EUR 2283.00
  • EUR 586.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Caveolin 1 (CAV1) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Caveolin 1 (CAV1) ELISA Kit

SEA214Mu-10x96wellstestplate 10x96-wells test plate
EUR 4391.16
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Caveolin 1 (CAV1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Caveolin 1 (CAV1) ELISA Kit

SEA214Mu-1x48wellstestplate 1x48-wells test plate
EUR 449.27
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Caveolin 1 (CAV1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Caveolin 1 (CAV1) ELISA Kit

SEA214Mu-1x96wellstestplate 1x96-wells test plate
EUR 598.96
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Caveolin 1 (CAV1) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Taken collectively, our findings recommend that ASLD is a singular genetic mannequin for learning NO-dependent osteoblast operate and that the NO-glycolysis pathway could also be a brand new goal to modulate bone anabolism. An affiliation between periodontitis and atherosclerosis (AS) has been established. P. gingivalis is a key pathogen of periodontitis that promotes foam cell formation by regulating actions of CD36 scavenger receptors expressed on the macrophages. LIMP2, a member of CD36 superfamily, is concerned in ldl cholesterol efflux. However, whether or not LIMP2 is concerned in the formation of froth cells promoted by P. gingivalis stays unclear.