Familial hyperckemia and calf hypertrophy secondary to a caveolin-3 mutation

Idiopathic hyperckemia has been described as persistent serum creatine kinase (CK) elevation at the least 1.5 occasions the higher restrict of regular in people with in any other case regular laboratory findings and neurological examination. This kind of hyperckemia encompasses each sporadic and familial instances, which have been discovered to be asymptomatic or sub-clinical, presenting with gentle signs, similar to myalgias or cramps. Genetic causes of hyperckemia have been not often described. The authors intention to describe a benign autosomal dominant situation brought on by a uncommon mutation within the caveolin geneCaveolin gene encodes for structural membrane proteins in muscle.

The phenotypes of 22 sufferers with both an ARID2 heterozygous mutation or haploinsufficiency have been reviewed. Comprehensive molecular analyses have been carried out utilizing somatic and induced pluripotent stem cells (iPSCs) of a affected person with ARID2 haploinsufficiency in addition to utilizing the mouse mannequin of Arid2 haploinsufficiency by CRISPR/Cas9 gene enhancing. The phenotypic traits of ARID2 deficiency embrace RASopathy, Coffin-Lowy syndrome or Coffin-Siris syndrome or undefined syndromic ID.
Transient ARID2 knockout HeLa cells utilizing an shRNA elevated ERK1 and ERK2 phosphorylation. Impaired neuronal differentiation with enhanced RAS-MAPK exercise was noticed in patient-iPSCs. In addition, Arid2 haploinsufficient mice exhibited lowered physique dimension and studying/reminiscence deficit. ARID2 haploinsufficiency was related to lowered IFITM1 expression, which interacts with caveolin-1 (CAV-1) and inhibits ERK activation.
Duck meat is taken into account a delicacy, however selecting the very best meat is problematic. Caveolin-3 (CAV-3) is a muscle-specific protein marker in animals. The objective of the present research was to detect the traits of Cav-3 gene in geese. 2. Full-length Cav-3 was acquired from geese (Anas platyrhynchos) utilizing reverse transcriptase PCR and speedy amplification of cDNA ends. DNAMAN software program was used for homology comparisons. Quantitative reverse transcription-PCR, PCR-single-strand conformation polymorphism, and sequencing have been used to decide Cav-3 expression and polymorphism of a single nucleotide, respectively.

Caveolin-3: A Causative Process of Chicken Muscular Dystrophy

The etiology of hen muscular dystrophy is the synthesis of aberrant WW area containing E3 ubiquitin-protein ligase 1 (WWP1) protein made by a missense mutation of WWP1 gene. The β-dystroglycan that confers stability to sarcolemma was recognized as a substrate of WWP protein, which induces the subsequent molecular collapse. The aberrant WWP1 will increase the ubiquitin ligase-mediated ubiquitination following extreme degradation of sarcolemmal and cytoplasmic β-dystroglycan, and an erased β-dystroglycan in dystrophic αW fibers will lead to molecular imperfection of the dystrophin-glycoprotein advanced (DGC).

The DGC is a core protein of costamere that’s a necessary a part of power transduction and protects the muscle fibers from contraction-induced harm. Caveolin-3 (Cav-3) and dystrophin bind competitively to the identical web site of β-dystroglycan, and extreme Cav-Three on sarcolemma will block the interplay of dystrophin with β-dystroglycan, which is another excuse for the disruption of the DGC. It is understood that fast-twitch glycolytic fibers are extra delicate and weak to contraction-induced small tears than slow-twitch oxidative fibers below a number of diseased situations.

Despite their rising relevance to absolutely perceive illness pathogenesis, we have now as but a poor understanding as to how biomechanical indicators are built-in with particular biochemical pathways to decide cell behaviour. Mesothelial-to-mesenchymal transition (MMT) markers colocalized with TGF-β1-dependent signaling and yes-associated protein (YAP) activation throughout biopsies from totally different pathologies exhibiting peritoneal fibrosis, supporting mechanotransduction as a central driving element of those class of fibrotic lesions and its crosstalk with particular signaling pathways.

Transcriptome and proteome profiling of the response of mesothelial cells (MCs) to linear cyclic stretch revealed molecular adjustments appropriate with bona fide MMT, which (i) overlapped with established YAP goal gene subsets, and have been largely depending on endogenous TGF-β1 signaling. Importantly, TGF-β1 blockade blunts the transcriptional upregulation of those gene signatures, however not the mechanical activation and nuclear translocation of YAP per se. We studied the function therein of caveolin-1 (CAV1), a plasma membrane mechanotransducer.

Familial hyperckemia and calf hypertrophy secondary to a caveolin-3 mutation

Adiponectin is secreted through caveolin 1-dependent mechanisms in white adipocytes

Here we have now investigated the function of the protein caveolin 1 (Cav1) and caveolae within the secretion of the white adipocyte hormone adiponectin. Using mouse major subcutaneous adipocytes genetically depleted of Cav1, we present that the adiponectin secretion, stimulated both adrenergically or by insulin, is abrogated whereas basal (unstimulated) launch of adiponectin is elevated. Adiponectin secretion is equally affected in wildtype mouse and human adipocytes the place the caveolae construction was chemically disrupted.

The altered ex vivo secretion in adipocytes remoted from Cav1 null mice is accompanied by lowered serum ranges of the high-molecular weight (HMW) type of adiponectin whereas the whole focus of adiponectin is unaltered. Interestingly, ranges of HMW adiponectin are maintained in adipose tissue from Cav1-depleted mice, signifying that a secretory defect is current. The gene expression of key regulatory proteins recognized to be concerned in cAMP/adrenergically triggered adiponectin exocytosis (the beta Three adrenergic receptor and trade protein instantly activated by cAMP) stays intact in Cav1 null adipocytes.

Anti- Caveolin-1 (CAV1) Antibody

GWB-84CF33 0.05 mg Ask for price

Anti- Caveolin-1 (CAV1) Antibody

GWB-C2E1AD 0.05 mg Ask for price

Anti- Caveolin-1 (CAV1) Antibody

GWB-D4B933 0.05 mg Ask for price

Anti-human Caveolin-1 antibody

A1506-50 each
EUR 561.6

Caveolin 1 antibody

20R-1949 50 ug
EUR 269
Description: Rabbit polyclonal Caveolin 1 antibody

Caveolin 1 antibody

20R-2291 50 ug
EUR 269
Description: Rabbit polyclonal Caveolin 1 antibody

Caveolin 1 Antibody

E18-5372-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Caveolin 1 Antibody

E18-5372-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Caveolin 1 Antibody

E38PA1160 100ul
EUR 225
Description: Available in various conjugation types.

Caveolin 1 Antibody

E38PA1161 100ul
EUR 225
Description: Available in various conjugation types.

Caveolin 1, Antibody

GWB-2C9A54 7 ml Ask for price

Caveolin 1, Antibody

GWB-2CB3DF 1 ml Ask for price

Caveolin 1 Antibody

AF0126 200ul
EUR 420

Caveolin 1 Antibody

AF5372 200ul
EUR 420

Caveolin 1 Antibody

AF5372-100ul 100ul
EUR 280

Caveolin 1 Antibody

AF5372-200ul 200ul
EUR 350

Caveolin 1 Antibody

AF6386 200ul
EUR 420

Caveolin 1 Antibody

AF6386-100ul 100ul
EUR 280

Caveolin 1 Antibody

AF6386-200ul 200ul
EUR 350

Caveolin 1 antibody

70R-35767 100 ug
EUR 294
Description: Rabbit polyclonal Caveolin 1 antibody

Caveolin 1 antibody

70R-49479 100 ul
EUR 242
Description: Purified Polyclonal Caveolin 1 antibody

Caveolin 1 antibody

70R-49480 100 ul
EUR 242
Description: Purified Polyclonal Caveolin 1 antibody

Caveolin 1 antibody

70R-31113 100 ug
EUR 294
Description: Rabbit polyclonal Caveolin 1 antibody

Caveolin 1 Antibody

ABF5372 100 ug
EUR 525.6

Caveolin- 1 Antibody

ABF6386 100 ug
EUR 525.6

Caveolin- 1 Antibody

ABF0126 100 ug
EUR 525.6

Caveolin 1, Antibody

GWB-DBA3FD 7 ml Ask for price

Caveolin 1 Antibody

GWB-81BDC8 0.1 mg Ask for price

Caveolin 1, Antibody

GWB-95A9FE 1 ml Ask for price

Caveolin 1 Antibody

R33422-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: CAV1

Caveolin-1 Antibody

33331-100ul 100ul
EUR 302.4

Caveolin-1 Antibody

33331-50ul 50ul
EUR 224.4

Caveolin-1 Antibody

48674-100ul 100ul
EUR 399.6

Caveolin-1 Antibody

48674-50ul 50ul
EUR 286.8

Caveolin-1 Antibody

E033331 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Caveolin-1 Antibody

E18-6386-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Caveolin-1 Antibody

E18-6386-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Caveolin-1 Antibody

E18-0126-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Caveolin-1 Antibody

E18-0126-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Caveolin-1 Antibody

E11-0139C 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Caveolin-1 Antibody

E80407-6 100μl
EUR 225
Description: Available in various conjugation types.

Caveolin-1 Antibody

E8M0407-28 100ul
EUR 225
Description: Available in various conjugation types.

Caveolin-1 Antibody

A1010-50 each
EUR 483.6

Caveolin-1 Antibody

8219-002mg 0.02 mg
EUR 206.18
Description: Caveolin-1 Antibody: Caveolin-1 is a scaffolding protein that is the main component of the caveolae plasma membranes found in most cell types (1). The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression (2). The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade (3). Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy (4).

Caveolin-1 Antibody

8219-01mg 0.1 mg
EUR 523.7
Description: Caveolin-1 Antibody: Caveolin-1 is a scaffolding protein that is the main component of the caveolae plasma membranes found in most cell types (1). The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression (2). The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade (3). Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy (4).

Caveolin-1 Antibody

8C0139 50ug
EUR 368
Description: Caveolin-1 Antibody

CAVEOLIN-1, Antibody

GWB-A9772C 0.1 mg Ask for price

Caveolin-1 Antibody

RQ4919 100 ug
EUR 356.15
Description: CAV1( Caveolin-1) is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms(alpha and beta) are encoded by a single transcript from this gene.

Caveolin-1 Antibody

R30587 100 ug
EUR 356.15
Description: CAV1, Caveolin-1, is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms(alpha and beta) are encoded by a single transcript from this gene.

Caveolin-1 Antibody

R31583 100 ug
EUR 356.15
Description: Caveolin-1 is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms(alpha and beta) are encoded by a single transcript from this gene.

Caveolin 1 antibody (Tyr14)

70R-35245 100 ug
EUR 294
Description: Purified Rabbit polyclonal Caveolin 1 antibody (Tyr14)

Caveolin 1 Antibody (Biotin)

abx431143-200ul 200 ul
EUR 460.8

Caveolin antibody

10R-10553 100 ug
EUR 344
Description: Mouse monoclonal Caveolin antibody

Caveolin Antibody

33331 100ul
EUR 319

Caveolin Antibody

48674 100ul
EUR 499

Anti- Caveolin-2 (CAV2) Antibody

GWB-E08C60 0.1 mg Ask for price

Caveolin-1 (CAV1) Antibody

abx231313-100ug 100 ug
EUR 577.2

Caveolin-1 (CAV1) Antibody

abx231314-100ug 100 ug
EUR 577.2

Caveolin-1 (CAV1) Antibody

20-abx137365
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  • 100 ug
  • 20 ug
  • 5 ug

Caveolin-1 (CAV1) Antibody

abx231313-100g 100 µg
EUR 350

Caveolin-1 (CAV1) Antibody

abx231314-100g 100 µg
EUR 350

Caveolin-1 (CAV1) Antibody

abx137365-01mg 0.1 mg
EUR 225

Caveolin-1 (CAV1) Antibody

abx341410-100g 100 µg Ask for price

Caveolin-1 (CAV1) Antibody

abx341410-20g 20 µg
EUR 250

Caveolin-1 (CAV1) Antibody

abx341410-50g 50 µg
EUR 350

Caveolin-1 (CAV1) Antibody

abx402136-100g 100 µg
EUR 287.5

Caveolin 1 Antibody (N-term)

GWB-B8D63C 0.05 mg Ask for price

Polyclonal Caveolin-1 Antibody

APG02445G 0.05ml
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caveolin-1 . This antibody is tested and proven to work in the following applications:

Polyclonal Caveolin-1 Antibody

APG02446G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caveolin-1 . This antibody is tested and proven to work in the following applications:

Caveolin 1 (CAV1) Antibody

20-abx327354
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  • Ask for price
  • 100 ug
  • 50 ug

Caveolin 1 (CAV1) Antibody

abx431142-200ul 200 ul
EUR 460.8

Caveolin 1 (CAV1) Antibody

20-abx328161
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  • Ask for price
  • 100 ug
  • 50 ug

Caveolin 1 (CAV1) Antibody

abx330500-100ul 100 ul
EUR 510

Caveolin 1 (CAV1) Antibody

abx332130-100ul 100 ul
EUR 510

Caveolin 1 (CAV1) Antibody

20-abx100474
  • Ask for price
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  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Caveolin 1 (CAV1) Antibody

20-abx100475
  • Ask for price
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  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Caveolin 1 (CAV1) Antibody

20-abx100476
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  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Caveolin 1 (CAV1) Antibody

20-abx175748
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  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx175750
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  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Caveolin 1 (CAV1) Antibody

20-abx175751
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  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx175752
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  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx175753
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx175754
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx175755
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx175756
  • Ask for price
  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx171646
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  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx171647
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  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx171648
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  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx171649
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  • Ask for price
  • 1 mg
  • 200 ug

Caveolin 1 (CAV1) Antibody

20-abx125305
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  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 50 ul

Caveolin 1 (CAV1) Antibody

20-abx241052
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  • Ask for price
  • 100 ul
  • 50 ul

Caveolin 1 (CAV1) Antibody

20-abx242330
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  • Ask for price
  • 100 ul
  • 50 ul

Caveolin 1 (CAV1) Antibody

abx122002-100ug 100 ug
EUR 469.2

Caveolin 1 (CAV1) Antibody

20-abx116788
  • Ask for price
  • Ask for price
  • 150 ul
  • 50 ul

Caveolin 1 (CAV1) Antibody

20-abx009491
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  • Ask for price
  • 100 ul
  • 200 ul
  • 30 ul

Caveolin 1 (CAV1) Antibody

20-abx009492
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  • Ask for price
  • 100 ul
  • 200 ul
  • 30 ul

Caveolin 1 (CAV1) Antibody

20-abx013031
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  • Ask for price
  • Ask for price
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Caveolin 1 (CAV1) Antibody

20-abx000539
  • Ask for price
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  • Ask for price
  • 100 ul
  • 200 ul
  • 50 ul

Caveolin 1 (CAV1) Antibody

abx019037-100ug 100 ug
EUR 410.4

Caveolin 1 (CAV1) Antibody

abx013031-100g 100 µg
EUR 237.5

Caveolin 1 (CAV1) Antibody

abx013031-10g 10 µg
EUR 43.75

Caveolin 1 (CAV1) Antibody

abx013031-200g 200 µg
EUR 312.5

Caveolin 1 (CAV1) Antibody

abx000539-100l 100 µl
EUR 400

Caveolin 1 (CAV1) Antibody

abx000539-20l 20 µl
EUR 175

Caveolin 1 (CAV1) Antibody

abx000539-50l 50 µl
EUR 275

Caveolin 1 (CAV1) Antibody

abx010494-100g 100 µg Ask for price

Caveolin 1 (CAV1) Antibody

abx010494-10g 10 µg
EUR 350

Caveolin 1 (CAV1) Antibody

abx010494-200g 200 µg Ask for price

Caveolin 1 (CAV1) Antibody

abx242330-96tests 96 tests
EUR 250

Caveolin 1 (CAV1) Antibody

abx116788-100g 100 µg
EUR 612.5

Caveolin 1 (CAV1) Antibody

abx122002-100l 100 µl Ask for price

Caveolin 1 (CAV1) Antibody

abx122002-20l 20 µl
EUR 337.5

Caveolin 1 (CAV1) Antibody

abx122002-50l 50 µl Ask for price

Caveolin 1 (CAV1) Antibody

abx100474-100l 100 µl
EUR 250

Caveolin 1 (CAV1) Antibody

abx100474-1ml 1 ml
EUR 675

Caveolin 1 (CAV1) Antibody

abx100474-200l 200 µl
EUR 312.5

Caveolin 1 (CAV1) Antibody

abx100475-100l 100 µl
EUR 262.5

Caveolin 1 (CAV1) Antibody

abx100475-1ml 1 ml
EUR 687.5

Caveolin 1 (CAV1) Antibody

abx100475-200l 200 µl
EUR 325

Caveolin 1 (CAV1) Antibody

abx100476-100l 100 µl
EUR 262.5

Caveolin 1 (CAV1) Antibody

abx100476-1ml 1 ml
EUR 725

Caveolin 1 (CAV1) Antibody

abx100476-200l 200 µl
EUR 337.5

Caveolin 1 (CAV1) Antibody

abx019037-1mg 1 mg
EUR 300

Caveolin 1 (CAV1) Antibody

abx241052-100l 100 µl
EUR 350

Caveolin 1 (CAV1) Antibody

abx241052-50l 50 µl
EUR 250

Caveolin 1 (CAV1) Antibody

abx175750-1096tests 10 × 96 tests
EUR 737.5

Caveolin 1 (CAV1) Antibody

abx175750-596tests 5 × 96 tests
EUR 337.5

Caveolin 1 (CAV1) Antibody

abx175750-96tests 96 tests
EUR 262.5

Caveolin 1 (CAV1) Antibody

abx171646-1ml 1 ml
EUR 712.5

Caveolin 1 (CAV1) Antibody

abx171648-1ml 1 ml
EUR 775

Caveolin 1 (CAV1) Antibody

abx327354-100g 100 µg
EUR 250

Caveolin 1 (CAV1) Antibody

abx327354-50g 50 µg
EUR 187.5

Caveolin 1 (CAV1) Antibody

abx431142-200l 200 µl
EUR 387.5

Caveolin 1 (CAV1) Antibody

abx328161-100g 100 µg
EUR 250

Caveolin 1 (CAV1) Antibody

abx328161-50g 50 µg
EUR 187.5

Recombinant Caveolin-1 Antibody

R20350-0.1ML 100ul
EUR 409

Goat Anti Caveolin 1 Polyclonal Antibody

CPBT-65031GC 0.1 mg
EUR 1033.2

Caveolin 3 Antibody

E19-7547-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

Caveolin 3 Antibody

E19-7547-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Caveolin 2 Antibody

E18-5409-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

Caveolin 2 Antibody

E18-5409-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Caveolin 3 Antibody

DF7547 200ul
EUR 420

Caveolin 3 Antibody

DF7547-100ul 100ul
EUR 280

Caveolin 3 Antibody

DF7547-200ul 200ul
EUR 350

Caveolin 2 Antibody

E38PA5497 100ul
EUR 225
Description: Available in various conjugation types.

Caveolin 2 Antibody

AF5409 200ul
EUR 420

Caveolin 2 Antibody

AF5409-100ul 100ul
EUR 280

Caveolin 2 Antibody

AF5409-200ul 200ul
EUR 350

Caveolin 3 Antibody

45063-100ul 100ul
EUR 302.4

Caveolin 3 Antibody

45063-50ul 50ul
EUR 224.4

Caveolin 2 antibody

70R-13173 100 ul
EUR 550
Description: Affinity purified Rabbit polyclonal Caveolin 2 antibody

Caveolin 3 Antibody

ABD7547 100 ug
EUR 525.6

Caveolin 2 Antibody

ABF5409 100 ug
EUR 525.6

Caveolin 3, Antibody

GWB-35F242 1 ml Ask for price

Caveolin 2 Antibody

GWB-F33B1A 0.025 mg Ask for price

Caveolin 1 (pY14) Antibody

E38PA3159 100ul
EUR 225
Description: Available in various conjugation types.

Caveolin 1 (pT14) Antibody

20-abx009682
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  • 100 ul
  • 200 ul
  • 30 ul

Caveolin 1 (pY14) Antibody

abx010493-100ug 100 ug
EUR 526.8

Caveolin-2 Antibody 

21687 100ul
EUR 319

Caveolin-2 Antibody 

21687-100ul 100ul
EUR 302.4

Caveolin-2 Antibody 

21687-50ul 50ul
EUR 224.4

caveolin-2 antibody

22980 100ul
EUR 479

caveolin-2 antibody

22980-100ul 100ul
EUR 468

Caveolin-2 Antibody

48770 100ul
EUR 499

Caveolin-2 Antibody

48770-100ul 100ul
EUR 399.6

Caveolin-2 Antibody

48770-50ul 50ul
EUR 286.8

Caveolin-3 Antibody

48771 100ul
EUR 499

Caveolin-3 Antibody

48771-100ul 100ul
EUR 399.6

Caveolin-3 Antibody

48771-50ul 50ul
EUR 286.8

Caveolin-2 Antibody

E021687 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Caveolin-2 Antibody

F54989-0.08ML 0.08 ml
EUR 140.25
Description: CAV2 is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor.

Caveolin-2 Antibody

F54989-0.4ML 0.4 ml
EUR 322.15
Description: CAV2 is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor.

Caveolin-2 Antibody

RQ5696 100 ug
EUR 356.15
Description: Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. It is mapped to 7q31.1-q31.2. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both of them are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury.

Caveolin-2 Antibody

R30617 100 ug
EUR 356.15
Description: Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of both are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.

Caveolin-2 Antibody

R31584 100 ug
EUR 356.15
Description: Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. It is mapped to 7q31.1-q31.2. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both of them are expressed in neuronal cells. CAV2 was upregulated in response to neuronal cell injury.

Caveolin-1 (CAV1) Antibody (HRP)

abx341411-100g 100 µg Ask for price

Caveolin-1 (CAV1) Antibody (HRP)

abx341411-20g 20 µg
EUR 250

Caveolin-1 (CAV1) Antibody (HRP)

abx341411-50g 50 µg
EUR 350

Caveolin-1 Polyclonal Antibody

40684-100ul 100ul
EUR 302.4

Caveolin-1 Polyclonal Antibody

40684-50ul 50ul
EUR 224.4

Caveolin-1 Polyclonal Antibody

E040684 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Caveolin-1 Polyclonal Antibody

E20-70685 100ug
EUR 225
Description: Available in various conjugation types.

Caveolin-1 Polyclonal Antibody

E20-70686 100ug
EUR 225
Description: Available in various conjugation types.

Caveolin-1 Conjugated Antibody

C48674 100ul
EUR 476.4

Caveolin-1 Polyclonal Antibody

ABP50873-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Caveolin-1 from Human, Mouse, Rat. This Caveolin-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Caveolin-1 around the non-phosphorylation site of Y14

Caveolin-1 Polyclonal Antibody

ABP50873-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Caveolin-1 from Human, Mouse, Rat. This Caveolin-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Caveolin-1 around the non-phosphorylation site of Y14

Caveolin-1 Polyclonal Antibody

ABP50873-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Caveolin-1 from Human, Mouse, Rat. This Caveolin-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Caveolin-1 around the non-phosphorylation site of Y14

Caveolin-1 Polyclonal Antibody

ABP50874-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Caveolin-1 from Human, Mouse, Rat. This Caveolin-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caveolin-1 at AA range: 100-180

Caveolin-1 Polyclonal Antibody

ABP50874-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Caveolin-1 from Human, Mouse, Rat. This Caveolin-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caveolin-1 at AA range: 100-180

Caveolin-1 Polyclonal Antibody

ABP50874-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Caveolin-1 from Human, Mouse, Rat. This Caveolin-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caveolin-1 at AA range: 100-180

Microscopy and fractionation research point out that adiponectin vesicles don’t co-localise with Cav1 however that some vesicles are related to a particular fraction of caveolae. Our research suggest that Cav1 has an vital function in secretion of HMW adiponectin, though adiponectin-containing vesicles usually are not clearly related to this protein. We counsel that Cav1, and/or the caveolae area, is important for organisation of signalling pathways concerned within the regulation of HMW adiponectin exocytosis, a operate that’s disrupted in Cav1/caveolae-depleted adipocytes.