Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes

CaveolinThree variants related to arrhythmogenic cardiomyopathy and muscular dystrophy can disrupt post-Golgi floor trafficking. As Caveolin1 was not too long ago recognized in cardiomyocytes, we hypothesize that conserved isoform-specific protein/protein interactions orchestrate distinctive cardiomyocyte microdomain capabilities. To analyze the Caveolin1 versus CaveolinThree interactome, we employed unbiased live-cell proximity proteomic, isoform-specific affinity, and complexome profiling mass spectrometry methods. We display the physiological relevance and loss-of-function mechanism of a novel CaveolinThree interactor in gene-edited human iPSC-cardiomyocytes.

To determine differential Caveolin1 versus CaveolinThree protein interactions and to outline the molecular foundation of cardiac CAV3 loss-of-function. Combining steady isotope labeling with proximity proteomics, we utilized mass spectrometry to display for putative CaveolinThree interactors in dwelling cardiomyocytes. Isoform-specific affinity proteomic and co-immunoprecipitation experiments confirmed the monocarboxylate transporter McT1 versus aquaporin1, respectively, as CaveolinThree or Caveolin1 particular interactors in cardiomyocytes. Superresolution STED microscopy confirmed distinct Caveolin1 versus CaveolinThree cluster distributions in cardiomyocyte transverse tubules.

CRISPR/Cas9-mediated CaveolinThree knock-out uncovered a stabilizing function for McT1 floor expression, proton-coupled lactate shuttling, elevated late Na+ currents, and early afterdepolarizations in human iPSC-derived cardiomyocytes. Complexome profiling confirmed that McT1 and the Na,Okay-ATPase kind labile protein assemblies with the multimeric CaveolinThree complicated. Combining the strengths of proximity and affinity proteomics, we recognized isoform-specific Caveolin1 versus CaveolinThree binding companions in cardiomyocytes.

McT1 represents a novel class of metabolically related Caveolin3-specific interactors near mitochondria in cardiomyocyte transverse tubules. CaveolinThree knock-out uncovered a beforehand unknown function for practical stabilization of McT1 in the floor membrane of human cardiomyocytes. Strikingly, CaveolinThree poor cardiomyocytes exhibit motion potential prolongation and instability, reproducing human reentry arrhythmias in silico. Given that lactate is a significant substrate for stress adaption each in the wholesome and the diseased human coronary heart, future research of conserved McT1/CaveolinThree interactions might present rationales to focus on this muscle-specific meeting operate therapeutically.

The Inflammatory Cytokine IL-3 Hampers Cardioprotection Mediated by Endothelial Cell-Derived Extracellular Vesicles Possibly by way of Their Protein Cargo

The organic relevance of extracellular vesicles (EV) launched in an ischemia/reperfusion setting remains to be unclear. We hypothesized that the inflammatory microenvironment prevents cardioprotection mediated by endothelial cell (EC)-derived extracellular vesicles. The results of naïve EC-derived EV (eEV) or eEV launched in response to interleukin-3 (IL-3) (eEV-IL-3) had been evaluated in cardiomyoblasts (H9c2) and rat hearts. In transwell assay, eEV protected the H9c2 uncovered to hypoxia/reoxygenation (H/R) extra effectively than eEV-IL-3.

Conversely, solely eEV instantly protected H9c2 cells to H/R-induced harm. Consistent with this latter remark, eEV, however not eEV-IL-3, exerted helpful results in the entire coronary heart. Protein profiles of eEV and eEV-IL-3, established utilizing label-free mass spectrometry, demonstrated that IL-Three drives adjustments in eEV-IL-Three protein cargo. Gene ontology evaluation revealed that each eEV and eEV-IL-Three had been geared up with full cardioprotective equipment, together with the Nitric Oxide Signaling in the Cardiovascular System. eEV-IL-Three had been additionally enriched in the endothelial-nitric oxide-synthase (eNOS)-antagonist caveolin-1 and proteins associated to the inflammatory response.

In vitro and ex vivo experiments demonstrated {that a} practical Mitogen-Activated Protein Kinase Kinase (MEK1/2)/eNOS/guanylyl-cyclase (GC) pathway is required for eEV-mediated cardioprotection. Consistently, eEV had been discovered enriched in MEK1/2 and in a position to induce the expression of B-cell-lymphoma-2 (Bcl-2) and the phosphorylation of eNOS in vitro. We conclude that an inflammatory microenvironment containing IL-Three adjustments the eEV cargo and impairs eEV cardioprotective motion.

Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes

Nitric oxide modulates bone anabolism by means of regulation of osteoblast glycolysis and differentiation

Previous research have proven that nitric oxide (NO) dietary supplements might stop bone loss and fractures in preclinical fashions of estrogen deficiency. However, the mechanisms by which NO modulates bone anabolism stay largely unclear. Argininosuccinate lyase (ASL) is the one mammalian enzyme able to synthesizing arginine, the only precursor for nitric oxide synthase (NOS)-dependent NO synthesis. Moreover, ASL can also be required for channeling extracellular arginine to NOS for NO manufacturing. ASL deficiency (ASLD) is thus a mannequin to check cell-autonomous, NOS-dependent NO deficiency.

Here, we report that lack of ASL led to decreased NO manufacturing and impairment of osteoblast differentiation. Mechanistically, the bone phenotype was a minimum of in half pushed by the lack of NO-mediated activation of the glycolysis pathway in osteoblasts that led to decreased osteoblast differentiation and performance. Heterozygous deletion of Caveolin-1, a unfavorable regulator of NO synthesis, restored NO manufacturing, osteoblast differentiation, glycolysis, and bone mass in a hypomorphic mouse mannequin of ASLD. The translational significance of those preclinical research was additional reiterated by research carried out in induced pluripotent stem cells (iPSCs) from a person with ASLD.

Rat Caveolin 1 ELISA kit

E02C0407-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin 1 ELISA kit

E01A10985 96T
EUR 700
Description: ELISA

Rat Caveolin 1 ELISA Kit

IRTCAV1KT each
EUR 718
Description: Rat Caveolin 1 ELISA Kit

Rat Caveolin-1 ELISA kit

E02C0700-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Rat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin-1 ELISA kit

E02C0700-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Rat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin-1 ELISA kit

E02C0700-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Rat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin-1 ELISA Kit

EK1495 96 tests
EUR 599

Rat Caveolin 1 ELISA Kit (CAV1)

RK03552 96 Tests
EUR 280

Rat CAV1(Caveolin 1) ELISA Kit

ELK2333-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CAV1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CAV1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat CAV1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat CAV1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat CAV1(Caveolin 1) ELISA Kit

ELK2333-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CAV1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CAV1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat CAV1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat CAV1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat Cav1/ Caveolin-1 ELISA Kit

E0163Ra 1 Kit
EUR 557
Description: Cav

Rat Cav-1(Caveolin-1) ELISA Kit

EKF57890-48T 48T
EUR 396.9

Rat Cav-1(Caveolin-1) ELISA Kit

EKF57890-5x96T 5x96T
EUR 2693.25

Rat Cav-1(Caveolin-1) ELISA Kit

EKF57890-96T 96T
EUR 567

Rat Cav-1(Caveolin-1) ELISA Kit

ER0256 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 9.375pg/ml

Rat CAV-1(Caveolin-1) ELISA Kit

RE2942R-48wells 48 wells
EUR 125.55

Rat CAV-1(Caveolin-1) ELISA Kit

RE2942R-96wells 96 wells
EUR 179.55

Rat Caveolin-1, CAV ELISA Kit

ELA-E0214r 96 Tests
EUR 1063.2

Cav-1 ELISA Kit| Rat Caveolin-1 ELISA Kit

EF017146 96 Tests
EUR 826.8

Rat Caveolin-1(Cav-1) Elisa Kit

EK720890 96 Wells
EUR 0.61

Rat Caveolin-1, Cav-1 ELISA KIT

CSB-E04837r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Caveolin-1, Cav-1 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Caveolin-1, Cav-1 ELISA KIT

1-CSB-E04837r
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Caveolin-1, Cav-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Caveolin-1,Cav-1 ELISA KIT

CN-02003R1 96T
EUR 553.2

Rat Caveolin-1(Cav-1)ELISA Kit

GA-E0362RT-48T 48T
EUR 380.4

Rat Caveolin-1(Cav-1)ELISA Kit

GA-E0362RT-96T 96T
EUR 595.2

Rat Caveolin-1(Cav-1)ELISA Kit

QY-E11290 96T
EUR 433.2

Rat Caveolin-1,Cav-1 ELISA Kit

SL0157Ra -
EUR 498

Rat Caveolin-1,Cav-1 ELISA KIT

YLA0922RA-48T 48T Ask for price

Rat Caveolin-1,Cav-1 ELISA KIT

YLA0922RA-96T 96T Ask for price

Rat Caveolin 1 (CAV1) ELISA Kit

abx256234-96tests 96 tests
EUR 848.4

Rat Caveolin 1 (CAV1) ELISA Kit

abx570323-96tests 96 tests
EUR 848.4

Rat Caveolin 1 (CAV1) ELISA Kit

20-abx155317
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Caveolin 1 (CAV1) ELISA Kit

DLR-CAV1-Ra 96T
EUR 454
Description: serum, plasma or other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

DLR-CAV1-Ra-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Caveolin 1 (CAV1) in samples from serum, plasma or other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

DLR-CAV1-Ra-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Rat Caveolin 1 (CAV1) in samples from serum, plasma or other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

EKN44163-48T 48T
EUR 370.02

Rat Caveolin 1 (CAV1) ELISA Kit

EKN44163-5x96T 5x96T
EUR 2510.85

Rat Caveolin 1 (CAV1) ELISA Kit

EKN44163-96T 96T
EUR 528.6

Rat Caveolin 1 (CAV1) ELISA Kit

EKU03052-48T 48T
EUR 542.78

Rat Caveolin 1 (CAV1) ELISA Kit

EKU03052-5x96T 5x96T
EUR 3683.15

Rat Caveolin 1 (CAV1) ELISA Kit

EKU03052-96T 96T
EUR 775.4

Rat Caveolin 1 (CAV1) ELISA Kit

DL-CAV1-Ra 96T
EUR 432
Description: serum, plasma or other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

EK13065 96Т
EUR 768

Rat Caveolin 1(CAV1) ELISA Kit

NSL0900r 96 Tests
EUR 498

Rat Caveolin 1 (CAV1)  ELISA Kit    

NSL1573r 96 Tests
EUR 498

Rat Caveolin 1 (CAV1) ELISA Kit

RD-CAV1-Ra-48T 48T
EUR 443.3
Description: serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

RD-CAV1-Ra-48Tests 48 Tests
EUR 613.2

Rat Caveolin 1 (CAV1) ELISA Kit

RD-CAV1-Ra-96T 96T
EUR 633.3
Description: serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

RD-CAV1-Ra-96Tests 96 Tests
EUR 850.8

Rat Caveolin 1 (CAV1) ELISA Kit

RDR-CAV1-Ra-48T 48T
EUR 465.47
Description: serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

RDR-CAV1-Ra-48Tests 48 Tests
EUR 640.8

Rat Caveolin 1 (CAV1) ELISA Kit

RDR-CAV1-Ra-96T 96T
EUR 664.97
Description: serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

RDR-CAV1-Ra-96Tests 96 Tests
EUR 890.4

Rat Caveolin 1 (CAV1) ELISA Kit

SEA214Ra-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Caveolin 1 (CAV1) in serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

SEA214Ra-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Caveolin 1 (CAV1) in serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

SEA214Ra-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Caveolin 1 (CAV1) in serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

SEA214Ra-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Caveolin 1 (CAV1) in serum, plasma and other biological fluids.

Rat Caveolin 1 (CAV1) ELISA Kit

4-SEA214Ra
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Caveolin 1 (CAV1) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.

Rat Caveolin 1 (CAV1) ELISA Kit

abx256234-1096tests 10 × 96 tests Ask for price

Rat Caveolin 1 (CAV1) ELISA Kit

abx256234-596tests 5 × 96 tests Ask for price

Rat Caveolin 1 (CAV1) ELISA Kit

abx155317-100g 100 µg
EUR 3212.5

Rat Caveolin 1 (CAV1) ELISA Kit

abx155317-50g 50 µg
EUR 675

Rat Caveolin-1,Cav-2 ELISA KIT

CN-02003R2 48T
EUR 372

ELISA kit for Rat CAV-1 (Caveolin-1)

E-EL-R0175 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Rat CAV-1 (Caveolin-1) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Rat CAV1 (Caveolin 1)

ELK2333 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Caveolin 1 from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Pig Caveolin 1 ELISA kit

E07C0407-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin 1 ELISA kit

E07C0407-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin 1 ELISA kit

E07C0407-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin 1 ELISA kit

E08C0407-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin 1 ELISA kit

E08C0407-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin 1 ELISA kit

E08C0407-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin 1 ELISA kit

E01A45897 96T
EUR 700
Description: ELISA

Goat Caveolin 1 ELISA kit

E06C0407-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin 1 ELISA kit

E06C0407-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin 1 ELISA kit

E06C0407-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin 1 ELISA Kit

IGTCAV1KT each
EUR 803
Description: Goat Caveolin 1 ELISA Kit

Human Caveolin 1 ELISA kit

E01A2223 96T
EUR 700
Description: ELISA

Mouse Caveolin 1 ELISA kit

E01A19726 96T
EUR 700
Description: ELISA

Mouse Caveolin 1 ELISA kit

E03C0407-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin 1 ELISA kit

E03C0407-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin 1 ELISA kit

E03C0407-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin 1 ELISA kit

E01C0407-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin 1 ELISA kit

E01C0407-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin 1 ELISA kit

E01C0407-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep Caveolin 1 ELISA kit

E01A98191 96T
EUR 700
Description: ELISA

Human Caveolin 1 ELISA Kit

IHUCAV1KT each
EUR 667
Description: Human Caveolin 1 ELISA Kit

Mouse Caveolin 1 ELISA Kit

IMSCAV1KT each
EUR 684
Description: Mouse Caveolin 1 ELISA Kit

Pig Caveolin-1 ELISA kit

E07C0700-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Porcine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin-1 ELISA kit

E07C0700-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Porcine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Caveolin-1 ELISA kit

E07C0700-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Porcine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin-1 ELISA kit

E08C0700-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Canine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin-1 ELISA kit

E08C0700-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Canine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Caveolin-1 ELISA kit

E08C0700-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Canine Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin 1 ELISA kit

E01A72043 96T
EUR 700
Description: ELISA

Canine Caveolin 1 ELISA kit

E01A63331 96T
EUR 700
Description: ELISA

Rabbit Caveolin 1 ELISA kit

E01A28465 96T
EUR 700
Description: ELISA

Bovine Caveolin 1 ELISA kit

E01A80761 96T
EUR 700
Description: ELISA

Rabbit Caveolin 1 ELISA kit

E04C0407-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin 1 ELISA kit

E04C0407-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin 1 ELISA kit

E04C0407-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin 1 ELISA kit

E09C0407-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin 1 ELISA kit

E09C0407-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin 1 ELISA kit

E09C0407-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Caveolin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine Caveolin 1 ELISA Kit

IBOCAV1KT each
EUR 786
Description: Bovine Caveolin 1 ELISA Kit

Canine Caveolin 1 ELISA Kit

ICNCAV1KT each
EUR 752
Description: Canine Caveolin 1 ELISA Kit

Goat Caveolin-1 ELISA kit

E06C0700-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Goat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin-1 ELISA kit

E06C0700-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Goat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Caveolin-1 ELISA kit

E06C0700-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Goat Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin 1 (CAV1) ELISA

KT-9647 96 tests
EUR 1032

Porcine Caveolin 1 ELISA kit

E01A54614 96T
EUR 700
Description: ELISA

Chicken Caveolin 1 ELISA kit

E01A89486 96T
EUR 700
Description: ELISA

Chicken Caveolin 1 ELISA Kit

ICHCAV1KT each
EUR 718
Description: Chicken Caveolin 1 ELISA Kit

Porcine Caveolin 1 ELISA Kit

IPCCAV1KT each
EUR 786
Description: Porcine Caveolin 1 ELISA Kit

Mouse Caveolin-1 ELISA kit

E03C0700-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Mouse Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin-1 ELISA kit

E03C0700-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Mouse Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Caveolin-1 ELISA kit

E03C0700-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Mouse Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin-1 ELISA kit

E01C0700-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Human Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin-1 ELISA kit

E01C0700-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Human Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Caveolin-1 ELISA kit

E01C0700-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Human Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin-1 ELISA kit

E04C0700-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Rabbit Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin-1 ELISA kit

E04C0700-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Rabbit Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Caveolin-1 ELISA kit

E04C0700-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Rabbit Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin-1 ELISA kit

E09C0700-192T 192 tests
EUR 1524
Description: A Sandwich ELISA for quantitative measurement of Monkey Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin-1 ELISA kit

E09C0700-48 1 plate of 48 wells
EUR 624
Description: A Sandwich ELISA for quantitative measurement of Monkey Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Caveolin-1 ELISA kit

E09C0700-96 1 plate of 96 wells
EUR 822
Description: A Sandwich ELISA for quantitative measurement of Monkey Caveolin-1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin 2(CAV2) ELISA kit

E01A11653 96T
EUR 700
Description: ELISA

Rat Caveolin 3(CAV3) ELISA kit

E01A11654 96T
EUR 700
Description: ELISA

Rat Caveolin 2(CAV2) ELISA kit

E02C1404-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Caveolin 2(CAV2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin 2(CAV2) ELISA kit

E02C1404-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Caveolin 2(CAV2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Caveolin 2(CAV2) ELISA kit

E02C1404-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Caveolin 2(CAV2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Taken collectively, our findings recommend that ASLD is a singular genetic mannequin for learning NO-dependent osteoblast operate and that the NO-glycolysis pathway could also be a brand new goal to modulate bone anabolism. An affiliation between periodontitis and atherosclerosis (AS) has been established. P. gingivalis is a key pathogen of periodontitis that promotes foam cell formation by regulating actions of CD36 scavenger receptors expressed on the macrophages. LIMP2, a member of CD36 superfamily, is concerned in ldl cholesterol efflux. However, whether or not LIMP2 is concerned in the formation of froth cells promoted by P. gingivalis stays unclear.