ACE2 Interaction Networks in COVID-19: A Physiological Framework for Prediction of Outcome in Patients with Cardiovascular Risk Factors

May 2, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) an infection (coronavirus illness 2019; COVID-19) is related with hostile outcomes in sufferers with heart problems (CVD). The purpose of the examine was to characterize the interplay between SARS-CoV-2 and Angiotensin-Converting Enzyme 2 (ACE2) purposeful networks with a concentrate on CVD. Using the community drugs strategy and publicly obtainable datasets, we investigated ACE2 tissue expression and described ACE2 interplay networks that could possibly be affected by SARS-CoV-2 an infection in the center, lungs and nervous system.
We in contrast them with modifications in ACE-2 networks following SARS-CoV-2 an infection by analyzing public information of human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). This evaluation was carried out utilizing the Network by Relative Importance (NERI) algorithm, which integrates protein-protein interplay with co-expression networks. We additionally carried out miRNA-target predictions to establish which miRNAs regulate ACE2-related networks and will play a job in the COVID19 final result. Finally, we carried out enrichment evaluation for figuring out the primary COVID-19 threat teams.
We discovered related ACE2 expression confidence ranges in respiratory and cardiovascular methods, supporting that coronary heart tissue is a possible goal of SARS-CoV-2. Analysis of ACE2 interplay networks in contaminated hiPSC-CMs recognized a number of hub genes with corrupted signaling which could be accountable for cardiovascular signs. The most affected genes had been EGFR (Epidermal Growth Factor Receptor), FN1 (Fibronectin 1), TP53, HSP90AA1, and APP (Amyloid Beta Precursor Protein), whereas probably the most affected interactions had been related with MAST2 and CALM1 (Calmodulin 1).
Enrichment evaluation revealed a number of ailments related with the interplay networks of ACE2, particularly cancerous ailments, weight problems, hypertensive illness, Alzheimer’s illness, non-insulin-dependent diabetes mellitus, and congestive coronary heart failure. Among affected ACE2-network elements related with the SARS-Cov-2 interactome, we recognized AGT (Angiotensinogen), CAT (Catalase), DPP4 (Dipeptidyl Peptidase 4), CCL2 (C-C Motif Chemokine Ligand 2), TFRC (Transferrin Receptor) and CAV1 (Caveolin-1), related with cardiovascular threat elements.
We described for the primary time miRNAs which had been widespread regulators of ACE2 networks and virus-related proteins in all analyzed datasets. The high miRNAs regulating ACE2 networks had been miR-27a-3p, miR-26b-5p, miR-10b-5p, miR-302c-5p, hsa-miR-587, hsa-miR-1305, hsa-miR-200b-3p, hsa-miR-124-3p, and hsa-miR-16-5p. Our examine gives an entire mechanistic framework for investigating the ACE2 community which was validated by expression information. This framework predicted threat teams, together with the established ones, thus offering dependable novel info concerning the complexity of signaling pathways affected by SARS-CoV-2. It additionally recognized miRNAs that could possibly be used in personalised prognosis in COVID-19.
ACE2 Interaction Networks in COVID-19: A Physiological Framework for Prediction of Outcome in Patients with Cardiovascular Risk Factors

Treatment of keloids by Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway

Keloids are a pores and skin fibroproliferative situation characterised by the hyperproliferation of fibroblasts and the extreme deposition of extracellular matrix (ECM) elements. Previous research have decided that Caveolin‑1 managed hyperresponsiveness to mechanical stimuli by Runt‑associated transcription issue 2 (Runx2) activation in keloids. However, the molecular mechanism of Runx2 regulating the pathological development of keloids has not been elucidated. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) evaluation revealed that the majority of the differentially expressed genes (DEGs), together with Runx2, had been considerably enriched in the organic processes

Positive regulation of cell proliferation’, in the mobile elements ‘Extracellular matrix’, in the molecular features ‘Extracellular matrix structural constituents’ and in the KEGG ‘PI3K‑Akt signaling pathway’. The purpose of the current examine was to research the expression ranges of the Runx2 in human keloid tissues and first human keloid fibroblasts (HKFs), and to find out the underlying molecular mechanisms concerned in the fibrotic roles of Runx2 in keloid formation. Runx2 expression ranges had been analyzed in affected person keloid tissues and HKFs utilizing western blotting, reverse transcription‑quantitative PCR (RT‑qPCR) and immunofluorescence microscopy.

Primary HKFs had been transfected with a small interfering RNA (si) particularly concentrating on Runx2 (si‑Runx2). Subsequently, Cell Counting Kit‑8, wound therapeutic and Transwell assays, movement cytometry, RT‑qPCR and western blotting had been utilized to judge the proliferation, migration, apoptosis, ECM deposition and PI3K/AKT signaling pathway of HKFs, respectively. In addition, western blotting was additionally used to find out the expression ranges of phosphorylated AKT and PI3K in HKFs. The outcomes revealed that Runx2 expression ranges had been upregulated in keloid tissues and first HKFs in contrast with the conventional pores and skin tissues and human regular fibroblasts.

Following the transfection with si‑Runx2, the proliferative and migratory skills of HKFs had been considerably lowered and the apoptotic charge was elevated. The expression ranges of kind I, kind III collagen, fibronectin, and α‑easy muscle actin had been downregulated in si‑Runx2‑transfected cells, which was hypothesized to happen by following the downregulation of the phosphorylation ranges of PI3K and AKT. In conclusion, the findings of the current examine indicated that Runx2 silencing in HKFs may considerably inhibit the cell proliferation, migration and the expression ranges of ECM‑associated proteins, and promote apoptosis by way of suppressing the PI3K/AKT signaling pathway.

CAV1 Polyclonal Antibody
E91555 100ul
EUR 225
Description: Available in various conjugation types.

CAV1 Polyclonal Antibody
E90059a 100ul
EUR 225
Description: Available in various conjugation types.

CAV1 Polyclonal Antibody
ABP-PAB-31007 50 ug Ask for price

CAV1 Polyclonal Antibody
ABP-PAB-31008 50 ug Ask for price

CAV1 Polyclonal Antibody
ABP-PAB-31009 50 ug Ask for price

CAV1 Rabbit Polyclonal Antibody
54051 100ul
EUR 439

CAV1 Rabbit Polyclonal Antibody
E10G04673 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

CAV1 Rabbit Polyclonal Antibody
E10G11547 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Caveolin 1 (CAV1) Polyclonal Antibody
CAU28340-100ul 100ul
EUR 229.4

Caveolin 1 (CAV1) Polyclonal Antibody
CAU28340-200ul 200ul
EUR 287.3

Caveolin 1 (CAV1) Polyclonal Antibody
CAU28341-100ul 100ul
EUR 217.9

Caveolin 1 (CAV1) Polyclonal Antibody
CAU28341-200ul 200ul
EUR 272.2

Caveolin 1 (CAV1) Polyclonal Antibody
CAU28342-100ul 100ul
EUR 212.2

Caveolin 1 (CAV1) Polyclonal Antibody
CAU28342-200ul 200ul
EUR 265.4

Caveolin 1 (CAV1) Polyclonal Antibody
CAU30985-100ul 100ul
EUR 232.3

Caveolin 1 (CAV1) Polyclonal Antibody
CAU30985-200ul 200ul
EUR 290.6

Rabbit Anti-Human CAV1 (aa 12-16) Polyclonal Antibody
CPB-1020RH 100 ul
EUR 552

Caveolin-1 (CAV1) Rabbit anti-Human Polyclonal Antibody
GWB-106B42 0.05 mg Ask for price

Caveolin-1 (CAV1) Rabbit anti-Human Polyclonal Antibody
GWB-F5D255 0.05 mg Ask for price

Caveolin-1 (CAV1) Rabbit anti-Human Polyclonal Antibody
GWB-FF1B2C 0.05 mg Ask for price

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse)
4-PAA214Mu01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Caveolin 1 (CAV1)

Rabbit Anti-Human CAV1 Polyclonal Antibody, Phospho-Tyr14
CPB-654RH 100 ul
EUR 670.8

Polyclonal CAV1 / Caveolin 1 Antibody (Internal)
APG02439G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human CAV1 / Caveolin 1 (Internal). This antibody is tested and proven to work in the following applications:

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse), PE
4-PAA214Mu01-PE
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Caveolin 1 (CAV1). This antibody is labeled with PE.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse), APC
4-PAA214Mu01-APC
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Caveolin 1 (CAV1). This antibody is labeled with APC.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse), Cy3
4-PAA214Mu01-Cy3
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Caveolin 1 (CAV1). This antibody is labeled with Cy3.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse), HRP
4-PAA214Mu01-HRP
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Caveolin 1 (CAV1). This antibody is labeled with HRP.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse, Rat)
4-PAA214Ra01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Caveolin 1 (CAV1)

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse), FITC
4-PAA214Mu01-FITC
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Caveolin 1 (CAV1). This antibody is labeled with FITC.

Caveolin 1 (CAV1) Polyclonal Antibody (Human, Mouse)
4-PAA214Hu01
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Caveolin 1 (CAV1)

Caveolin-1 (CAV1) Goat anti-Human Polyclonal (Internal) Antibody
GWB-B18F13 0.05 mg Ask for price

Polyclonal CAV1 / Caveolin 1 Antibody (aa1-104)
APG02436G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CAV1 / Caveolin 1 (aa1-104). This antibody is tested and proven to work in the following applications:

Polyclonal CAV1 / Caveolin 1 Antibody (aa2-104)
APG02438G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CAV1 / Caveolin 1 (aa2-104). This antibody is tested and proven to work in the following applications:

Polyclonal CAV1 / Caveolin 1 Antibody (aa129-178)
APG02437G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CAV1 / Caveolin 1 (aa129-178). This antibody is tested and proven to work in the following applications:

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse, Rat), PE
4-PAA214Ra01-PE
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Caveolin 1 (CAV1). This antibody is labeled with PE.

Polyclonal CAV1 / Caveolin 1 Antibody (N-Terminus)
APG02440G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human CAV1 / Caveolin 1 (N-Terminus). This antibody is tested and proven to work in the following applications:

Polyclonal CAV1 / Caveolin 1 Antibody (N-Terminus)
APG02441G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CAV1 / Caveolin 1 (N-Terminus). This antibody is tested and proven to work in the following applications:

Polyclonal CAV1 / Caveolin 1 Antibody (N-Terminus)
APG02442G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CAV1 / Caveolin 1 (N-Terminus). This antibody is tested and proven to work in the following applications:

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse, Rat), APC
4-PAA214Ra01-APC
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Caveolin 1 (CAV1). This antibody is labeled with APC.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse, Rat), Cy3
4-PAA214Ra01-Cy3
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Caveolin 1 (CAV1). This antibody is labeled with Cy3.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse, Rat), HRP
4-PAA214Ra01-HRP
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Caveolin 1 (CAV1). This antibody is labeled with HRP.

Caveolin 1 (CAV1) Polyclonal Antibody (Human, Mouse), PE
4-PAA214Hu01-PE
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Caveolin 1 (CAV1). This antibody is labeled with PE.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse, Rat), FITC
4-PAA214Ra01-FITC
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Caveolin 1 (CAV1). This antibody is labeled with FITC.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse), Biotinylated
4-PAA214Mu01-Biotin
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Caveolin 1 (CAV1). This antibody is labeled with Biotin.

Caveolin 1 (CAV1) Polyclonal Antibody (Human, Mouse), APC
4-PAA214Hu01-APC
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Caveolin 1 (CAV1). This antibody is labeled with APC.

Caveolin 1 (CAV1) Polyclonal Antibody (Human, Mouse), Cy3
4-PAA214Hu01-Cy3
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Caveolin 1 (CAV1). This antibody is labeled with Cy3.

Caveolin 1 (CAV1) Polyclonal Antibody (Human, Mouse), HRP
4-PAA214Hu01-HRP
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Caveolin 1 (CAV1). This antibody is labeled with HRP.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse), APC-Cy7
4-PAA214Mu01-APC-Cy7
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Caveolin 1 (CAV1). This antibody is labeled with APC-Cy7.

Caveolin 1 (CAV1) Polyclonal Antibody (Human, Mouse), FITC
4-PAA214Hu01-FITC
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Caveolin 1 (CAV1). This antibody is labeled with FITC.

Caveolin 1 (CAV1) rabbit polyclonal antibody, Aff - Purified
AP02643PU-N 100 µg Ask for price

Caveolin 1 (CAV1) rabbit polyclonal antibody, Aff - Purified
AP02643PU-S 50 µg Ask for price

Caveolin 1 (CAV1) rabbit polyclonal antibody, Aff - Purified
AP06040PU-N 100 µg Ask for price

Caveolin 1 (CAV1) rabbit polyclonal antibody, Aff - Purified
AP06041PU-N 100 µg Ask for price

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse, Rat), Biotinylated
4-PAA214Ra01-Biotin
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Caveolin 1 (CAV1). This antibody is labeled with Biotin.

Caveolin 1 (CAV1) Polyclonal Antibody (Mouse, Rat), APC-Cy7
4-PAA214Ra01-APC-Cy7
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Caveolin 1 (CAV1). This antibody is labeled with APC-Cy7.

Polyclonal Anti-CAV1 Antibody
GWB-BBP391 0.1 mg Ask for price

Caveolin 1 (CAV1) Polyclonal Antibody (Human, Mouse), Biotinylated
4-PAA214Hu01-Biotin
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Caveolin 1 (CAV1). This antibody is labeled with Biotin.

Caveolin 1 (CAV1) Polyclonal Antibody (Human, Mouse), APC-Cy7
4-PAA214Hu01-APC-Cy7
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Caveolin 1 (CAV1). This antibody is labeled with APC-Cy7.

Caveolin 1 (CAV1) (C-term) rabbit polyclonal antibody, Purified
AP31042PU-N 250 µl Ask for price

Caveolin 1 (CAV1) (Internal) goat polyclonal antibody, Aff - Purified
AP07517PU-N 50 µg Ask for price

Caveolin 1 (CAV1) pTyr14 rabbit polyclonal antibody, Aff - Purified
AP02388PU-N 100 µg Ask for price

Caveolin 1 (CAV1) pTyr14 rabbit polyclonal antibody, Aff - Purified
AP02388PU-S 50 µg Ask for price

Caveolin 1 (CAV1) pTyr14 rabbit polyclonal antibody, Aff - Purified
AP01544PU-N 100 µg Ask for price

Goat Polyclonal Anti-CAV1 Antibody
AB0055-200 400 µg Ask for price

Anti- Cav1b Polyclonal Antibody
AB3G241 0.1mg
EUR 399

Rabbit Polyclonal Anti-CAV1 Antibody
TA350951 100 µl Ask for price

Rabbit Polyclonal Anti-CAV1 Antibody
TA330176 100 µl Ask for price

Rabbit Polyclonal Anti-CAV1 Antibody
TA330401 100 µl Ask for price

CaVα2δ1 Polyclonal Antibody
E20-53494 100ug
EUR 225
Description: Available in various conjugation types.

CaVα2δ2 Polyclonal Antibody
E20-53495 100ug
EUR 225
Description: Available in various conjugation types.

CaVα2δ3 Polyclonal Antibody
E20-53539 100ug
EUR 225
Description: Available in various conjugation types.

CaVα2δ3 Polyclonal Antibody
E44H11162 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

CaVα2δ1 Polyclonal Antibody
E44H11117 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

CaVα2δ2 Polyclonal Antibody
E44H11118 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Rabbit Polyclonal antibody to Caveolin 2 (caveolin 2)
TA308863 100 µl Ask for price

Polyclonal CaV1.3 Antibody
APG02444G 0.05ml
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CaV1.3 . This antibody is tested and proven to work in the following applications:

Rabbit Polyclonal Anti-CAV1 Antibody (N-Terminus)
TA341088 50 µg Ask for price

Rabbit Polyclonal Anti-CAV1 Antibody (N-Terminus)
TA341089 50 µg Ask for price

Rabbit Polyclonal Anti-CAV1 Antibody (N-Terminus)
TA341090 50 µg Ask for price

Cav1.2 Polyclonal Antibody
E20-53534 100ug
EUR 225
Description: Available in various conjugation types.

Cav1.3 Polyclonal Antibody
E20-53535 100ug
EUR 225
Description: Available in various conjugation types.

Cav2.2 Polyclonal Antibody
E20-53536 100ug
EUR 225
Description: Available in various conjugation types.

Cav3.2 Polyclonal Antibody
E20-53537 100ug
EUR 225
Description: Available in various conjugation types.

Cav3.3 Polyclonal Antibody
E20-53538 100ug
EUR 225
Description: Available in various conjugation types.

Cav1.2 Polyclonal Antibody
ABP57305-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cav1.2 from Human, Mouse, Rat. This Cav1.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav1.2 Polyclonal Antibody
ABP57305-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cav1.2 from Human, Mouse, Rat. This Cav1.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav1.2 Polyclonal Antibody
ABP57305-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cav1.2 from Human, Mouse, Rat. This Cav1.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav1.3 Polyclonal Antibody
ABP57306-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cav1.3 from Human, Mouse, Rat. This Cav1.3 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav1.3 Polyclonal Antibody
ABP57306-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cav1.3 from Human, Mouse, Rat. This Cav1.3 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav1.3 Polyclonal Antibody
ABP57306-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cav1.3 from Human, Mouse, Rat. This Cav1.3 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav1.3 Polyclonal Antibody
ABP57306-100uL 100 μL
EUR 239
Description: Rabbit Anti-Cav1.3 Polyclonal Antibody

Cav1.3 Polyclonal Antibody
ABP57306-200uL 200 μL
EUR 379
Description: Rabbit Anti-Cav1.3 Polyclonal Antibody

Cav1.3 Polyclonal Antibody
ABP57306-30uL 30 μL
EUR 109
Description: Rabbit Anti-Cav1.3 Polyclonal Antibody

Cav2.2 Polyclonal Antibody
ABP57307-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cav2.2 from Human, Mouse, Rat. This Cav2.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav2.2 Polyclonal Antibody
ABP57307-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cav2.2 from Human, Mouse, Rat. This Cav2.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav2.2 Polyclonal Antibody
ABP57307-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cav2.2 from Human, Mouse, Rat. This Cav2.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav3.2 Polyclonal Antibody
ABP57308-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cav3.2 from Human, Mouse, Rat. This Cav3.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav3.2 Polyclonal Antibody
ABP57308-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cav3.2 from Human, Mouse, Rat. This Cav3.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav3.2 Polyclonal Antibody
ABP57308-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cav3.2 from Human, Mouse, Rat. This Cav3.2 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav3.3 Polyclonal Antibody
ABP57309-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Cav3.3 from Human, Mouse, Rat. This Cav3.3 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav3.3 Polyclonal Antibody
ABP57309-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Cav3.3 from Human, Mouse, Rat. This Cav3.3 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav3.3 Polyclonal Antibody
ABP57309-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Cav3.3 from Human, Mouse, Rat. This Cav3.3 antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthetic peptide

Cav1.2 Polyclonal Antibody
E44H11157 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Cav1.3 Polyclonal Antibody
E44H11158 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Cav2.2 Polyclonal Antibody
E44H11159 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Cav3.2 Polyclonal Antibody
E44H11160 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Cav3.3 Polyclonal Antibody
E44H11161 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

CaVα2δ1 Rabbit Polyclonal Antibody
E12-469 100μg/100μl
EUR 255
Description: Available in various conjugation types.

CaVα2δ2 Rabbit Polyclonal Antibody
E12-470 100μg/100μl
EUR 255
Description: Available in various conjugation types.

CaVα2δ3 rabbit polyclonal antibody
E12-514 100ug/100ul
EUR 255
Description: Available in various conjugation types.

CaVα2δ1 Rabbit Polyclonal Antibody
EA267-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against CaV?2?1 from Rat. This antibody is tested and validated for WB, ELISA, IHC

CaVα2δ1 Rabbit Polyclonal Antibody
EA267-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against CaV?2?1 from Rat. This antibody is tested and validated for WB, ELISA, IHC

CaVα2δ2 Rabbit Polyclonal Antibody
EA268-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against CaV?2?2 from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

CaVα2δ2 Rabbit Polyclonal Antibody
EA268-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against CaV?2?2 from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA, IHC

CaVα2δ3 Rabbit Polyclonal Antibody
EA274-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against CaV?2?3 from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA

CaVα2δ3 Rabbit Polyclonal Antibody
EA274-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against CaV?2?3 from Human/ Rat/ Mouse. This antibody is tested and validated for WB, ELISA

CaVα2δ1 Rabbit Polyclonal Antibody
ES8296-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against CaV?2?1 from Rat. This antibody is tested and validated for WB, ELISA, IHC

CaVα2δ1 Rabbit Polyclonal Antibody
ES8296-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against CaV?2?1 from Rat. This antibody is tested and validated for WB, ELISA, IHC

CaVα2δ2 Rabbit Polyclonal Antibody
ES8297-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against CaV?2?2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC

CaVα2δ2 Rabbit Polyclonal Antibody
ES8297-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against CaV?2?2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC

CaVα2δ3 Rabbit Polyclonal Antibody
ES8303-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against CaV?2?3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA

CaVα2δ3 Rabbit Polyclonal Antibody
ES8303-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against CaV?2?3 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA

Polyclonal human CaV1.2 Antibody
APR07894G 0.05ml
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human human CaV1.2 . This antibody is tested and proven to work in the following applications:

Goat Anti Caveolin 1 Polyclonal Antibody
CPBT-65031GC 0.1 mg
EUR 1033.2

CaVα2δ1 Rabbit Polyclonal Antibody(A193)
RA20210-100ul 100 ul
EUR 298

CaVα2δ1 Rabbit Polyclonal Antibody(A193)
RA20210-50ul 50 ul
EUR 198

CaVα2δ2 Rabbit Polyclonal Antibody(A194)
RA20211-100ul 100 ul
EUR 298

CaVα2δ2 Rabbit Polyclonal Antibody(A194)
RA20211-50ul 50 ul
EUR 198

CaVα2δ3 Rabbit Polyclonal Antibody(A210)
RA20217-100ul 100 ul
EUR 298

CaVα2δ3 Rabbit Polyclonal Antibody(A210)
RA20217-50ul 50 ul
EUR 198

Cav1.2 rabbit polyclonal antibody
E12-509 100ug/100ul
EUR 255
Description: Available in various conjugation types.

Cav1.3 rabbit polyclonal antibody
E12-510 100ug/100ul
EUR 255
Description: Available in various conjugation types.

This paper aimed to discover the genome-wide DNA methylation standing of methamphetamine (MA) abusers with completely different qualities to habit and to establish differentially methylated candidate genes. A complete of 207 male MA abusers with an MA abuse frequency of ≥10 instances and an MA abuse length of ≥1 12 months had been assigned to the excessive MA habit high quality group (HMAQ group; 168 topics who met the diagnostic standards for MA dependence in response to the DSM-IV) or to the low MA addictive high quality group (LMAQ group; 39 topics who didn’t meet the factors for MA dependence). In addition 105 wholesome controls had been recruited.